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KMID : 0362919880060020253
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Journal of the Korean Society for Therapeutic Radiology and Oncology
1988 Volume.6 No. 2 p.253 ~ p.258
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The Radiation Effect on Peripheral Blood Cell
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Lee Tae-June
Kwon Hyoung-Cheol
Kim Jung-Soo
Im Sun-Kyun
Choi Ki-Cheol
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Abstract
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To evaluate radiation effect on the hematopoietic system, we analyzed 44 patients who were treated with conventionally fractionated radiation therapy (RT) at Chonbuk National University Hospital.
According to the treatment sites, we classified them into three groups: group I as head and neck, group Ⅱ as thorax, and group Ⅲ as pelvis.
White blood cell, lymphocyte, platelet and hemoglobin were checked before and during RT
The results were as follow;
1. White blood cell (WBC) and lymphocyte count were declined from the first week of RT to the third week, and then slightly recovered after the third or fourth week. There was prominent decrease in lymphocyte counts than WBC.
2. Platelet counts were declined until the second week of the RT, showed slight recovery at fourth week in all groups. Hemoglobin values were slightly decreased in the first week and then recovered the level of pretreatment value, gradually.
3. Lymphocyte count were declined significantly on group Ⅲ(p<0.01), WBC and platelet counts were decreased on group Ⅱ but statistically not significant.
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KEYWORD
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Hematopoietic system, Radiation Therapy
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